This is frequently referred to "cubing the up" and it is a common way to get to the next level rune without the need to hunt for this in nature d2r items for sale. For instance, if you are carrying three El runes, but you require an Eld rune, put three El runes in the cube and hit the transmute button. Out will pop and out will pop an Eld rune. This recipe for upgrading is available in the rune chart below.
The quest for Hellforge found in Act 4 will always drop certain runes. The quest is often used as payment for the speed of the actions. The Countess's abode, at the at the bottom of the Forgotten Tower in Act 1's Black Marsh, is another fantastic source of runes.Because runs have a particular limit of rarity.
Which ranges from most commonly used (El) through to the rarest (Zod) and are frequently employed as the currency in Diablo 2. El up to Lem are typically considered low runes. Pul to Gul are generally considered to be mid runes, and Vex through Zod are typically considered to be high runes. If you come across high or mid runes on your travels, be sure not to sell them quickly!
Runewords are some of the most impressive items that you can create during Diablo 2: Resurrected, although they require quite some effort to make buy diablo II resurrected items. You first need to locate the appropriate runes for the runeword. Afterwards, you'll need the weapon, shield, or armor that can accommodate the runeword.